There are 6 real estate agents found in De Soto, MO. View our De Soto real estate area information to learn about the weather, local school districts, demographic data, and general information about De Soto, MO. Get in touch with a De Soto real estate agent who can help you find the home of your dreams in De Soto. Use our mortgage calculator to see how much it would be to finance a home in De Soto. Not ready to buy yet? Find and compare apartments for rent in De Soto.