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643 Grand Avenue, South San Francisco, CA 94080

South San Francisco
Local realty services provided by:CENTURY 21 Epic
643 Grand Avenue,South San Francisco, CA 94080
$1,248,000
  • 3 Beds
  • 4 Baths
  • 1,630 sq. ft.
  • Single family
  • Active
Listed by: jill penna
Office: christie's international real estate sereno
MLS#:ML82059314
Source:Bay East, CCAR, bridgeMLS

Price summary

  • Price:$1,248,000
  • Price per sq. ft.:$765.64

About this home

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

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Home facts

  • Year built:1895
  • Listing ID #:ML82059314
  • Added:13 day(s) ago
  • Updated:September 11, 2026 at 06:01 AM

Rooms and interior

  • Bedrooms:3
  • Total bathrooms:4
  • Full bathrooms:4
  • Living area:1,630 sq. ft.

Heating and cooling

  • Heating:Forced Air

Structure and exterior

  • Year built:1895
  • Building area:1,630 sq. ft.
  • Lot area:0.08 Acres
  • Foundation Description:Slab

Utilities

  • Water:Public

Finances and disclosures

  • Price:$1,248,000
  • Price per sq. ft.:$765.64

Features and amenities

  • Appliances:Water Softener
  • Amenities:Water Softener

Parking

  • Garage:Yes
  • Garage spaces:2
MLS LogoBay East 2026. CCAR 2026 bridgeMLS 2026. Information Deemed Reliable But Not Guaranteed. This information is being provided by the Bay East MLS, or CCAR MLS, or bridgeMLS. The listings presented here may or may not be listed by the Broker/Agent operating this website. This information is intended for the personal use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Data last updated at September 11, 2026 CAMAXMLS Member Broker: Mike Southwick

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